Pharmacokinetic and metabolism studies u
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Blaire L. Osborn; Fred P. Abramson
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Article
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1998
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John Wiley and Sons
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English
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We present a novel method for performing pharmacokinetic and metabolism studies on macromolecules that offers advantages over the existing techniques of radiolabeling, immunoassay or bioassays. Our strategy uses macromolecules with stable isotopes uniformly distributed throughout the structure. The