Theoretical studies on pyridoxal 5′-phos
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Rong-Zhen Liao; Wan-Jian Ding; Jian-Guo Yu; Wei-Hai Fang; Ruo-Zhuang Liu
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Article
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2008
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John Wiley and Sons
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English
⚖ 595 KB
## Abstract Density functional methods have been applied to investigate the irreversible transamination between glyoxylic acid and pyridoxamine analog and the catalytic mechanism for the critical [1,3] proton transfer step in aspartate aminotransferase (AATase). The results indicate that the cataly