Transactions on Computational Systems Biology XI

✍ Scribed by Muffy Calder, Jane Hillston (auth.), Corrado Priami, Ralph-Johan Back, Ion Petre (eds.)

• Publisher: Springer Berlin Heidelberg
• Year: 2009
• Tongue: English
• Leaves: 343
• Series: Lecture Notes in Computer Science 5750 : Transactions on Computational Systems Biology
• Category: Library

✦ Synopsis

The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena.

This special issue on Computational Models for Cell Processes is based on a workshop with the same name that took place in Turku, Finland, on May 27, 2008. The accepted papers, which have passed through a separate peer-review process, span an interesting mix of approaches to systems biology, ranging from quantitative to qualitative techniques, from continuous to discrete mathematics, from deterministic to stochastic methods, and from computational models for biology to computing paradigms inspired by biology. Also included in this issue are three regular submissions dealing with the relationship between ODEs and stochastic concurrent constraint programming, with the equilibrium points of genetic regulatory networks, and with probability models describing how epigenetic context affects gene expression and organismal development.

✦ Table of Contents

Front Matter....Pages -
Process Algebra Modelling Styles for Biomolecular Processes....Pages 1-25
Simple, Enhanced and Mutual Mobile Membranes....Pages 26-44
Bio-PEPA with Events....Pages 45-68
In Silico Modelling and Analysis of Ribosome Kinetics and aa-tRNA Competition....Pages 69-89
Qualitative and Quantitative Analysis of a Bio-PEPA Model of the Gp130/JAK/STAT Signalling Pathway....Pages 90-115
Rule-Based Modelling and Model Perturbation....Pages 116-137
Extended Stochastic Petri Nets for Model-Based Design of Wetlab Experiments....Pages 138-163
A Projective Brane Calculus with Activate, Bud and Mate as Primitive Actions....Pages 164-186
Accepting Networks of Non-inserting Evolutionary Processors....Pages 187-199
Discrete Modeling of Biochemical Signaling with Memory Enhancement....Pages 200-215
Dynamical Systems and Stochastic Programming: To Ordinary Differential Equations and Back....Pages 216-267
Computing Equilibrium Points of Genetic Regulatory Networks....Pages 268-282
Code, Context, and Epigenetic Catalysis in Gene Expression....Pages 283-334
Back Matter....Pages -

✦ Subjects

Computational Biology/Bioinformatics; Simulation and Modeling; Computation by Abstract Devices; Artificial Intelligence (incl. Robotics); Algorithm Analysis and Problem Complexity; Probability and Statistics in Computer Science