Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes

All-trans retinoic acid attenuates ultra

All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes

✍ Cong Cao; Shu Wan; Qin Jiang; Ashley Amaral; Shan Lu; Gang Hu; Zhigang Bi; Nicol 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 574 KB

## Abstract One of the major characteristics of human skin photoaging induced by ultraviolet (UV) radiation is the dehydration of the skin. Water movement across plasma membrane occurs via diffusion through lipid bilayer and via aquaporins (AQPs). We find that UV induces aquaporin‐3 (AQP3) down‐reg