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Trans-synaptic regulation of tyrosine 3-mono-oxygenase biosynthesis in rat adrenal medulla

✍ Scribed by Alessandro Guidotti; Erminio Costa

Book ID: 115773679
Publisher: Elsevier Science
Year: 1977
Tongue: English
Weight: 990 KB
Volume: 26
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(77)90393-8

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## Abstract Reserpine treatment leads to a trans‐synaptic increase of the tyrosine hydroxylase (TH) gene transcription rate, mRNA and protein levels in catecholaminergic tissues including the adrenal medulla (AM) and the superior cervical ganglia (SCG). The TPA‐responsive element plays an important