𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Trans glutaminase-mediated cross-linking in mammalian epidermis

✍ Scribed by Joseph A. Rothnagel; George E. Rogers

Book ID
104678567
Publisher
Springer
Year
1984
Tongue
English
Weight
509 KB
Volume
58
Category
Article
ISSN
0300-8177

No coin nor oath required. For personal study only.

✦ Synopsis

The epsilon-(gamma-glutamyl)lysine isopeptide bond has been identified in certain structural proteins of the hair fibre and the epidermis. The major cross-linked proteins are not keratins and generally have little or no cysteine, but have a high glutamic acid/glutamine residue content. In the hair fibre the cross-link appears in the citrulline-containing proteins of the medulla and the inner root sheath of the follicle. In the epidermis the cross-linked proteins are involved in the formation of the cornified envelope of the stratum corneum cells. In both cases, the cross-linked proteins contribute the characteristic property of chemical resistance to their biological structures.

πŸ“œ SIMILAR VOLUMES

Initiation of DNA interstrand cross-link
Initiation of DNA interstrand cross-link repair in mammalian cells
✍ Erica M. Hlavin; Michael B. Smeaton; Paul S. Miller πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 447 KB πŸ‘ 1 views

## Abstract Interstrand cross‐links (ICLs) are among the most cytotoxic DNA lesions to cells because they prevent the two DNA strands from separating, thereby precluding replication and transcription. Even though chemotherapeutic cross‐linking agents are well established in clinical use, and numero

Metal-Mediated Cross-Linking in the Gene
Metal-Mediated Cross-Linking in the Generation of a Marine-Mussel Adhesive
✍ Mary J. Sever; Jaime T. Weisser; Jennifer Monahan; Shalini Srinivasan; Jonathan πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 218 KB πŸ‘ 2 views

Zuschriften Marine Muscheln heften sich mit einem proteinbasierten Klebstoff an OberflΓ€chen. Nach Untersuchungen am "Muschelkleber", dem extrahierten Protein und Peptidmodellen beruht die HΓ€rte dieses verbreiteten biologischen Materials auf einer Vernetzung durch [Fe(dopa) 3 ]-Komplexe. Mehr zu dies