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TRAIL receptor signalling and modulation: Are we on the right TRAIL?

โœ Scribed by Devalingam Mahalingam; Eva Szegezdi; Maccon Keane; Steven de Jong; Afshin Samali

Book ID
116395375
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
342 KB
Volume
35
Category
Article
ISSN
0305-7372

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## Abstract Apoptosis is an endogenous process that can be a useful antiโ€cancer tool. This study aimed to investigate the effect of Clโ€IBโ€MECA, adenosine receptor A3 agonist, on TRAILโ€induced apoptosis of thyroid carcinoma cells. Clโ€IBโ€MECA enhanced TRAILโ€mediated apoptosis in FRO but not in ARO ce