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TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract

✍ Scribed by Anil Sadarangani; Sumie Kato; Natalia Espinoza; Soledad Lange; Carmen Llados; Marisol Espinosa; Manuel Villalón; Stanley Lipkowitz; Mauricio Cuello; Gareth I. Owen

Publisher: Springer
Year: 2006
Tongue: English
Weight: 696 KB
Volume: 12
Category: Article
ISSN: 1360-8185
DOI: 10.1007/s10495-006-0492-z

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## Abstract Nitric oxide (NO) from astrocytes is one of the signalers used by the brain's extensive glial‐neuronal‐vascular network, but its excessive production by pro‐inflammatory cytokine‐stimulated glial cells can be cytodestructive. Here, we show how three pro‐inflammatory cytokines (IL‐1β, TN