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TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo

✍ Scribed by Perlstein, B.; Finniss, S. A.; Miller, C.; Okhrimenko, H.; Kazimirsky, G.; Cazacu, S.; Lee, H. K.; Lemke, N.; Brodie, S.; Umansky, F.; Rempel, S. A.; Rosenblum, M.; Mikklesen, T.; Margel, S.; Brodie, C.


Book ID
118005977
Publisher
Duke University Press
Year
2012
Tongue
English
Weight
687 KB
Volume
15
Category
Article
ISSN
1522-8517

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## Abstract Malignant gliomas are angiogenesis dependent and present a remarkable degree of resistance to radiotherapy. In the present work, we studied the effect of irradiation of C6 glioma cells on their proliferation and activation __in vitro__ and on glioma cell‐induced angiogenesis __in vivo__