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Traffic of prion protein between different compartments on the neuronal surface, and the propagation of prion disease

✍ Scribed by Roger J. Morris; Celia J. Parkyn; Angela Jen

Book ID
116466889
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
308 KB
Volume
580
Category
Article
ISSN
0014-5793

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## Abstract A synthetic peptide corresponding to the 106–126 amyloidogenic region of the cellular human prion protein (PrP^c^) is useful for in vitro study of prion‐induced neuronal cell death. The aim of the present work was to examine the implication of the cellular prion protein in the toxicity