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TRAF2 Is Essential for TNF-α-Induced Osteoclastogenesis

✍ Scribed by Kiyoshi Kanazawa; Akira Kudo


Book ID
111485225
Publisher
American Society for Bone and Mineral Research
Year
2004
Tongue
English
Weight
856 KB
Volume
20
Category
Article
ISSN
0884-0431

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## Abstract Particle‐induced periprosthetic osteolysis is the major cause for orthopedic implant failure. This failure is mediated mainly by the action of osteoclasts, the principal cells responsible for bone resorption and osteolysis. Therapeutic interventions to alleviate osteolysis have been foc