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Traditional Morita–Baylis–Hillman reaction of aldehydes with methyl vinyl ketone co-catalyzed by triphenylphosphine and nitrophenol

✍ Scribed by Shi, Min; Liu, Ying-Hao


Book ID
115479555
Publisher
Royal Society of Chemistry
Year
2006
Tongue
English
Weight
115 KB
Volume
4
Category
Article
ISSN
1477-0520

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Lewis base and l-proline co-catalyzed Ba
✍ Min Shi; Jian-Kang Jiang; Chao-Qun Li 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 63 KB

In the Baylis-Hillman reaction of arylaldehydes with methyl vinyl ketone, we found that, in the presence of a catalytic amount of L-proline, weak Lewis bases such as imidazole and triethylamine as well as the stronger Lewis base DABCO, can promote the Baylis-Hillman reaction to give the normal Bayli