Traditional Chinese medicine on four patients with Huntington's disease

✍ Scribed by Takashi Satoh; Toshiyuki Takahashi; Koh Iwasaki; Hideaki Tago; Takashi Seki; Nobuo Yaegashi; Muneshige Tobita; Hiroyuki Arai

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 905 KB
• Volume: 24
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/mds.22447

✦ Synopsis

Abstract

Four Huntington's disease (HD) patients were treated with traditional Chinese medicines Yi‐Gan San (YGS) and Chaihu‐Jia‐Longgu‐Muli Tan (CLMT) in a cross‐over manner. Two patients took YGS for 8 weeks first, and after 4 weeks of washing out, they took CLMT for 8 weeks. Two other patients took these medicines in reverse order. All patients showed a decrease in the Unified Huntington's Disease Rating Scale—motor assessment (from 106.3 ± 4.7 to 89.6 ± 5.8 as mean ± SD, P = 0.0004) by YGS treatment with no extrapiramidal symptoms or changes of cognition or ADL. Our study suggests a possibility of a new treatment for involuntary movements. © 2009 Movement Disorder Society