Post-thymic in vivo proliferation of nai
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Siegfried Kohler; Ulf Wagner; Matthias Pierer; Sonja Kimmig; Birgit Oppmann; Bea
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Article
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2005
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John Wiley and Sons
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English
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In spite of thymic involution early in life, the numbers of naive CD4(+) T cells only slowly decline in ageing humans implying peripheral post-thymic naive CD4(+) T cell expansion. This proliferation may compensate for continuous activation and death of naive CD4(+) T cells but may also have negativ