## Abstract The diagnosis of AD is still largely based on exclusion criteria of secondary causes and other forms of dementia with similar clinical pictures, than the diagnostic accuracy of AD is low. Improved methods of early diagnosis are needed, particularly because drugs treatment is more effect
โฆ LIBER โฆ
Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231
โ Scribed by Harald Hampel; Katharina Buerger; Russell Kohnken; Stefan J. Teipel; Raymond Zinkowski; Hans-Juergen Moeller; Stanley I. Rapoport; Peter Davies
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 909 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0364-5134
- DOI
- 10.1002/ana.111
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We surveyed a total of 570 cerebrospinal fluid (CSF) samples from a variety of diseases, including Alzheimer's disease (AD; n = 236), non-AD-demented and nondemented diseases (n = 239), and normal controls (n = 95) to quantitate levels of tau protein phosphorylated at serine 199 (CSF/phospho-tau199)