Trace element burdening of human tissues due to the corrosion of hip-joint prostheses made of cobalt-chromium alloys
✍ Scribed by R. Michel; J. Hofmann; F. Löer; J. Zilkens
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 928 KB
- Volume
- 103
- Category
- Article
- ISSN
- 1434-3916
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✦ Synopsis
Using instrumental neutron activation analysis, the concentrations of 18 elements were studied in human articular capsule and fascia lata before and after application of total endoprostheses of the hip joint made of cobalt-chromium alloys Tissues from the vicinity of the implant showed extreme burdening by corrosion products (Co, Cr, Ni), as well as by Zr, Hf, and Ba from the bone cements Tissues more distant from the implants exhibited lower, but still significant burdening Moreover, some essential trace elements not contained in the implant materials were changed in the tissues after implantation In order to clarify the dissolution of alloy constituents in biological media, the passivation of cobalt-chromium alloy was investigated by tracer techniques using Ringer's solution as a simple model of the body fluids The passivation process lasted for more than 1 month and was accompanied by a selective dissolution of the alloys constituents in the order Ni > Co Fe > Mo > Cr A comparison of the tissue analyses with the corrosion experiments demonstrates that the distribution patterns of the corrosion products in the tissues are influenced by both the corrosion process and the biochemical properties of the corrosion products.
Zusammenfassung
Fiir 18 Elemente wurde die Spurenelementzusammensetzung menschlicher Gewebe (Gelenkkapsel des Hiiftgelenks und Fascia lata) mit Hilfe instrumenteller Neutronenaktivierungsanalyse vor und nach Anwendung von Totalendoprothesen des Hiiftgelenks aus Kobalt-Chrom-Legierungen untersucht Die Gewebe aus der Umgebung der Implantate zeigten extreme Belastungen mit Korro-* Dedicated to Prof Dr Jrg Rehn on the occasion of his 66th birthday ** Supported in part by the Bundesminister fir Forschung und Technologie, Bonn, project "Radionuklidtechnik" and by the Deutsche Forschungsgemeinschaft, Bonn