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TPH2 polymorphisms and alcohol-related suicide

✍ Scribed by Tomaž Zupanc; Peter Pregelj; Martina Tomori; Radovan Komel; Alja Videtič Paska

Book ID
116772861
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
138 KB
Volume
490
Category
Article
ISSN
0304-3940

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## Abstract The TPH1 and TPH2 genes encode the rate‐limiting enzymes that control serotonin biosynthesis, and serotonin is clearly altered in autism. In the current study, eight SNPs in the TPH1 gene region and eight SNPs within the TPH2 gene were examined by family‐based association tests in a lar