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TPA induces subcellular translocation and subsequent down-regulation of both phorbol ester binding and protein kinase C activities in MCF-7 cells

✍ Scribed by Jean-Marie Darbon; Florence Oury; Simone Clamens; Francis Bayard


Book ID
115760279
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
529 KB
Volume
146
Category
Article
ISSN
0006-291X

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Protein kinase C activation and down-reg
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The role of protein kinase C activation in changes in muscarinic receptor functions and in the appearance of biochemical properties characteristic of neuronal cells was studied in SH-SY5Y human neuroblastoma cells induced to differentiate with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (