TP53 mutations and abnormal p53 protein staining in breast carcinomas related to prognosis
✍ Scribed by S. Thorlacius; B. Thorgilsson; J. Björnsson; L. Tryggvadottir; A.-L. Börresen; H.M. Ögmundsdottir; J.E. Eyfjörd
- Book ID
- 116166505
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 813 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0959-8049
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Formalin‐fixed, paraffin‐embedded biopsies of 193 women with primary breast cancer followed‐up for over 10 years were analysed immunohistochemically for the expression of p53 protein. Altogether, 58% (113/193) of the tumors were positive for p53 protein. Over‐expression of p53 was assoc
Epidemiological studies have suggested that dietary factors may differently affect p53-dependent and p53-independent pathways to colon cancer. Results of such studies may depend on the method used to assess p53 status. This case-control study of 185 colon-cancer cases and 259 controls examines this
## Abstract In 95 breast carcinomas, we investigated __P14ARF__ and __TP73__ mRNA expression and their relationship to __TP53__ mutations, determined by an immunohistochemical method, studying several clinicopathologic features of the tumors. __P14ARF__ and __TP73__ mRNA levels were determined by s