Toxicology of vanadium compounds in diabetic rats: The action of chelating agents on vanadium accumulation
β Scribed by Jose L. Domingo; Mercedes Gomez; Domenec J. Sanchez; Juan M. Llobet; Carl L. Keen
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 895 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0300-8177
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π SIMILAR VOLUMES
Vanadium has been shown to have a number of insulin-like effects and has been demonstrated to be beneficial in the treatment of streptozotocin-diabetic rats when included in the drinking water. However, some signs of toxicity and vanadium accumulation in all analysed tissues were reported in vanadiu
The effects of the chelating agents Na,Ca-ethylendiaminetetraacetate (EDTA), Na,Ca-diethylentriaminepentaacetate (DTPA), L-cysteine, 4,5-dihydroxy-1,3-benzene-disulfonic acid (Tiron) and deferoxamine mesylate and the reducing agent ascorbic acid on the toxicity, excretion and distribution of i.p. in