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Toxicological evaluation of the hydro-alcohol extract of the dry leaves of Peumus boldus and boldine in rats

✍ Scribed by Edvaldo Rodrigues de Almeida; Antonio Mário Melo; Haroudo Xavier


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
47 KB
Volume
14
Category
Article
ISSN
0951-418X

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✦ Synopsis


The hydro-alcohol extract of the dry leaves of Peumus boldus and boldine, showed abortive and teratogenic action and changes in the blood levels of bilirubin, cholesterol, glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and urea in rats. The long term administration of the extract and boldine did not cause histological modification during a period of 90 days.


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