Haematological, biochemical and pathological effects in rats produced by the salt-tolerant plant Avicennia marina given at oral doses of 1 or 4 g kg ؊1 for three consecutive days or 0.5 g kg ؊1 day ؊1 for 28 consecutive days are reported. No overt behavioral changes, moribundity or mortality were se
Toxicological evaluation of the hydro-alcohol extract of the dry leaves of Peumus boldus and boldine in rats
✍ Scribed by Edvaldo Rodrigues de Almeida; Antonio Mário Melo; Haroudo Xavier
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 47 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
The hydro-alcohol extract of the dry leaves of Peumus boldus and boldine, showed abortive and teratogenic action and changes in the blood levels of bilirubin, cholesterol, glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and urea in rats. The long term administration of the extract and boldine did not cause histological modification during a period of 90 days.
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