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Toxicokinetics of metformin-associated lactic acidosis with continuous renal replacement therapy

✍ Scribed by Mujtaba, Muhammad; Geara, Abdallah Sassine; Madhrira, Machaiah; Agarwala, Rajesh; Anderson, Herman; Cheng, Jen-Tse; Mohan, Sumit


Book ID
118303206
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
303 KB
Volume
37
Category
Article
ISSN
0378-7966

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## Abstract In this article, we discuss the case of a 42‐year‐old female diabetic patient who developed severe lactic acidosis, coma, shock, rhabdomyolysis, and renal and hepatic failure during metformin therapy after alcohol abuse. The APACHE II score of this patient was 38, which is associated wi