Toxicity of cotton phytoalexins to zoopathogenic fungi

✍ Scribed by Dr. Marshall E. Mace; Robert D. Stipanovic; Alois A. Bell

• Book ID: 102551890
• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 162 KB
• Volume: 1
• Category: Article
• ISSN: 1056-9014
• DOI: 10.1002/nt.2620010507

✦ Synopsis

The sesquiterpenoid phytoalexins desoxyhemigossypol, desoxymethoxyhemigossypol, and hemigossypolone formed in cotton (Gossypiuurr hirsutum and G. brbadensd stem xylem infected with Verttcillium dahliaewere shown to be highly toxic to zoopathogenic fungi. This appears to be the first study of the toxicity of terpenoid phytoalexins to zoopathogenic fungi. The toxicities of the phytoalexins expressed as MIC (pg ml -'>values were 8 to 128 against four isolates of Candida albicansand one isolate of Cr>/ptoca' cus neofurmans. These highly toxic compounds or their derivatives may prove useful for the treatment of animal mycoses.