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Toxicity of aliphatic amines: Structure-activity relationship

✍ Scribed by H. Greim; D. Bury; H.-J. Klimisch; M. Oeben-Negele; K. Ziegler-Skylakakis


Book ID
117250717
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
890 KB
Volume
36
Category
Article
ISSN
0045-6535

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The expiratory bradypnea indicative of upper airway irritation in mice was evaluated during a 15-min oronasal exposure to increasing concentrations of sixteen aliphatic amines. The airborne concentration resulting in a 50% decrease in the respiratory rate of mice ( R D ~~) was calculated for each te