Three patients developed fatal cardiac toxicity from the combination of cytosine arabinoside, cyclophosphamide, and total body irradiation while undergoing preparation for a bone marrow transplant. The pattern of the toxicity was unique for this combination of ablative chemotherapy. All three patien
β¦ LIBER β¦
Toxicity associated with high-dose cytosine arabinoside and total body irradiation as conditioning for allogeneic bone marrow transplantation
β Scribed by Kumar, M; Saleh, A; Rao, P V; Ochoa, S; Meyers, L; Miller, A; Graham-Pole, J
- Book ID
- 110010129
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 124 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0007-1188
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## Abstract Twenty children with acute leukemia between 3 and 19 years of age underwent allogeneic bone marrow transplantation from HLAβmatched sibling donors after conditioning with totalβbody irradiation (1,200 cGy in six fractions of 200 cGy twice daily for 3 days) and high dose cytosine arabino
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