Toxicity and feasibility of adjuvant high-dose interferon alpha-2b in patients with melanoma in clinical oncologic practice
โ Scribed by Ravaud, A; Bedane, C; Geoffrois, L; Lesimple, T; Delaunay, M
- Book ID
- 110002382
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 49 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0007-0920
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๐ SIMILAR VOLUMES
## Abstract ## BACKGROUND It has been shown that induction highโdose interferon ฮฑโ2b (IFNโฮฑโ2b) followed by maintenance therapy improves recurrenceโfree survival in adults with highโrisk, resected melanoma. In this study, the feasibility and toxicity of this regimen were evaluated in newly diagnos
## Abstract Interferon alpha is used for the adjuvant treatment of malignant melanoma at different dosages (highโ, intermediateโ, lowโdose therapy). Only a minority of patients might benefit from this therapy, and markers to identify such patients are missing. A recent study suggested that melanoma