𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Toxicarioside M, a new cytotoxic 10β-hydroxy-19-nor-cardenolide from Antiaris toxicaria

✍ Scribed by Claire Levrier; Bernard Kiremire; Françoise Guéritte; Marc Litaudon

Book ID
113624495
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
315 KB
Volume
83
Category
Article
ISSN
0367-326X

No coin nor oath required. For personal study only.

✦ Synopsis

A new 10β-hydroxy-19-nor-cardenolide, named toxicarioside M (1), was isolated from the trunk bark of Antiaris toxicaria (Pers.) Lesch (Moraceae), along with six known cardenolides (convallatoxin (2), convallatoxol (3), convalloside (4), 3-O-ß-D-xylopyranosylstrophanthidin (5), glucostrophanthidin (6) and strophanthidin ( 7)). Their structures were elucidated on the basis of HR-MS n analysis, spectroscopic methods (IR, UV, 1D and 2D NMR) and by comparison with data reported in the literature. The cardenolides were evaluated for their cytotoxic activity against KB, HCT-116, SF-268, MCF-7, HL-60, PC-3 and MRC-5 cell lines.

📜 SIMILAR VOLUMES

Toxicarioside A. A new cardenolide isola
Toxicarioside A. A new cardenolide isolated from Antiaris toxicaria latex-derived dart poison. Assignment of the 1H- and 13C-NMR shifts for an antiarigenin aglycone
✍ Christine A. Carter; Robert W. Forney; Elizabeth A. Gray; Amy M. Gehring; Tanya 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 628 KB

Bioassay-guided fractionation of the chloroform/methanol extract of a dart poison from Indonesian Borneo (Kalimantan), derived from Antiaris toxicaria latex, has led to the isolation of a new cardenolide, toxicarioside A [1]. The structure of 1 was deduced by analysis of spectroscopic data and has l

ChemInform Abstract: Toxicarioside A (I)
ChemInform Abstract: Toxicarioside A (I). A New Cardenolide Isolated from Antiaris toxicaria Latex-Derived Dart Poison. Assignment of the 1H- and 13C-NMR Shifts for an Antiarigenin Aglycone.
✍ C. A. CARTER; R. W. FORNEY; E. A. GRAY; A. M. GEHRING; T. L. SCHNEIDER; D. B. YO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v