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Toxic proteins released from mitochondria in cell death

โœ Scribed by Saelens, Xavier; Festjens, Nele; Walle, Lieselotte Vande; Gurp, Maria van; Loo, Geert van; Vandenabeele, Peter


Book ID
110068599
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
279 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract An increase in the permeability of the outer mitochondrial membrane is central to apoptotic cell death, since it leads to the release of several apoptogenic factors, such as cytochrome c and Smac/Diablo, into the cytoplasm that activate downstream death programs. During apoptosis, the m