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Toxic overdose of isoniazid, rifampicin and ethambutol

โœ Scribed by C. T. Spalding; W. C. Buss


Publisher
Springer
Year
1986
Tongue
English
Weight
296 KB
Volume
30
Category
Article
ISSN
0031-6970

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Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo