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Toxic effects of zearalenone and α-zearalenol on the regulation of steroidogenesis and testosterone production in mouse Leydig cells

✍ Scribed by Jianying Yang; Yongfa Zhang; Yongqiang Wang; Sheng Cui


Book ID
116919551
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
690 KB
Volume
21
Category
Article
ISSN
0887-2333

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## Abstract Zearalenone (ZEN) is a fusarotoxin converted predominantly into α‐zearalenol (α‐Zol) and β‐zearalenol (β‐Zol) by hepatic hydroxysteroid dehydrogenases. The feeding of naturally contaminated grains with ZEN was associated with hyperestrogenic and adverse effects on humans and animals. Th