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Toxic effect of an antitumor drug paclitaxel on morphofunctional characteristics of the liver in rats

✍ Scribed by L. A. Ermolaeva; T. Yu. Dubskaya; T. I. Fomina; T. V. Vetoshkina; V. E. Gol’dberg


Publisher
Springer US
Year
2008
Tongue
English
Weight
492 KB
Volume
145
Category
Article
ISSN
0007-4888

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Paclitaxel is an anticancer drug that has demonstrated severe embryotoxicity in chicks. This embryotoxicity is reduced by liposome encapsulation of the drug. The current study was designed to evaluate the potential of liposome encapsulation for reducing paclitaxel embryotoxicity in rats. Wistar rats