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Toxic effect of a β-amyloid peptide (β22–35) on the hippocampal neuron and its prevention

✍ Scribed by Takadera, Tsuneo; Sakura, Naoki; Mohri, Tetsuro; Hashimoto, Tadashi


Book ID
121414563
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
446 KB
Volume
161
Category
Article
ISSN
0304-3940

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## Abstract Male Wistar rats received unilateral intrahippocampal injections of 3 nmol (3.18 μg) aggregated Aβ(25–35), intracerebroventricular bilateral injections of 0.5 μg human recombinant TNFα or both (Aβ(25–35) + TNFα‐treated animals). Seven days after the surgery brain sections were stained w