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Towards optimal aqueous two-phase extraction system flowsheets for protein purification

✍ Scribed by Murni M. Ahmad; Todd M. Przybycien


Book ID
112120864
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
343 KB
Volume
88
Category
Article
ISSN
0268-2575

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Flowsheet simulation of aqueous two-phas
✍ Murni M. Ahmad; Steinar Hauan; Todd M. Przybycien πŸ“‚ Article πŸ“… 2010 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 381 KB πŸ‘ 1 views

## Abstract **BACKGROUND:** Aqueous two‐phase extraction (ATPE) has many advantages as an efficient, inexpensive large‐scale liquid–liquid extraction technique for protein separation. However, the realization of ATPE as a protein separation technology at industrial scales is rather limited due to t

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In this study we show that proteins can be partitioned and separated in a novel aqueous two-phase system composed of only one polymer in water solution. This system represents an attractive alternative to traditional two-phase systems which uses either two polymers (e.g., PEG/dextran) or one polymer