## Abstract **BACKGROUND:** Aqueous twoβphase extraction (ATPE) has many advantages as an efficient, inexpensive largeβscale liquidβliquid extraction technique for protein separation. However, the realization of ATPE as a protein separation technology at industrial scales is rather limited due to t
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Towards optimal aqueous two-phase extraction system flowsheets for protein purification
β Scribed by Murni M. Ahmad; Todd M. Przybycien
- Book ID
- 112120864
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2012
- Tongue
- English
- Weight
- 343 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0268-2575
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In this study we show that proteins can be partitioned and separated in a novel aqueous two-phase system composed of only one polymer in water solution. This system represents an attractive alternative to traditional two-phase systems which uses either two polymers (e.g., PEG/dextran) or one polymer