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Towards gene therapy for haemophilia B using primary human keratinocytes

✍ Scribed by Gerrard, Ann J.; Hudson, David L.; Brownlee, George G.; Watt, Fiona M.


Book ID
109915132
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
483 KB
Volume
3
Category
Article
ISSN
1061-4036

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## Abstract ## Background Keratinocytes are a very attractive vehicle for __ex vivo__ gene transfer and systemic delivery because proteins secreted by these cells may reach the circulation via a mechanism that mimics the natural process. ## Methods An efficient retroviral vector (LXSN) encoding