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Towards gene therapy for cystic fibrosis: a clinical progress report

✍ Scribed by Alton, E W F W; Geddes, D M; Gill, D R; Higgins, C F; Hyde, S C; Innes, J A; Porteous, D J


Book ID
110038212
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
28 KB
Volume
5
Category
Article
ISSN
0969-7128

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The success and validity of gene therapy and DNA vaccination in in vivo experiments and human clinical trials depend on the ability to produce large amounts of plasmid DNA according to defined specifications. A new method is described for the purification of a cystic fibrosis plasmid vector (pCF1-CF