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Towards establishing good practice in the use of computer prediction

โœ Scribed by Philip Neville Judson

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
69 KB
Volume
12
Category
Article
ISSN
1087-8378

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โœฆ Synopsis

Abstract

Recent developments in national and international legislation encourage the submission of computer predictions to support chemical registration, in order to reduce dependency on animal experiments. The Organisation for Economic Cooperation and Development (OECD) has issued guidelines for describing and evaluating such prediction models. This paper suggests that operating procedures and guidelines are needed for good practice in their development and application. Illustrative examples are provided of the sorts of issues that need to be considered and the possible rules that might be drawn up. Copyright ยฉ 2010 John Wiley & Sons, Ltd.

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