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Towards an understanding of the role of p53 in adrenocortical carcinogenesis

✍ Scribed by Jonathan D. Wasserman; Gerard P. Zambetti; David Malkin


Book ID
113796290
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
469 KB
Volume
351
Category
Article
ISSN
0303-7207

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Functional loss of the tumor suppressor p53 by alterations in its TP53 gene is a frequent event in cancers of different anatomical regions. Cervical cancer is strongly linked to infection by high-risk human papillomavirus (HPV) types. The viral oncoprotein E6 has the ability to associate with and ne