The role of TP53 in Cervical carcinogene
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Massimo Tommasino; Rosita Accardi; Sandra Caldeira; Wen Dong; Ilaria Malanchi; A
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Article
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2003
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John Wiley and Sons
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English
β 142 KB
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Functional loss of the tumor suppressor p53 by alterations in its TP53 gene is a frequent event in cancers of different anatomical regions. Cervical cancer is strongly linked to infection by high-risk human papillomavirus (HPV) types. The viral oncoprotein E6 has the ability to associate with and ne