Towards an optimized platform for the detection, enrichment, and semi-quantitation circulating tumor cells
✍ Scribed by T. J. Molloy; A. J. Bosma; Laura J. van’t Veer
- Book ID
- 106377759
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 307 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0167-6806
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## Abstract Detection of rare, circulating tumor cells (CTC's) in human peripheral blood is a potential indicator of prognosis and diagnosis in oncology. Typical methods to detect these CTC's are either by immunocytochemistry (ICCS) or RT‐PCR. However without accurate, rapid, and reproducible enric
Objectives: A major obstacle for permanent cancer eradication is the persistence of circulating tumor cells (CTCs) in blood, which often escape radio-or chemotherapy. Currently no efficient strategy to remove CTCs from peripheral blood in order to lower the risk of metastases or tumor recurrence exi