## Abstract 1,3‐Disubstituted tetrahydro‐oxazolo‐isoquinolinones **19a**,**b** were obtained from phenylalanine in seven steps and 42% overall yield by Katritzky’s benzotriazole method. The tricyclic oxazolidinone **19a** was further converted into amino alcohol **10** by employing a chemoselective
Towards a Total Synthesis of Quinocarcin: Diastereoselective Synthesis of Functionalized Azepino[1,2-b]isoquinolines.
✍ Scribed by Oliver Koepler; Sabine Laschat; Angelika Baro; Peter Fischer; Burkhard Miehlich; Marc Hotfilder; Christoph le Viseur
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 18 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract (__L__)‐Phenylalanine 4 can be converted to __N__‐(4‐methyl‐3‐pentenyl)tetrahydrosisoquinoline‐3‐carbaldehyde 10 and the corresponding homologous aldehyde 19 in 4 and 5 steps, respectively, by employing the Pictet–Spengler reaction as the key step. After Lewis acid catalyzed cyclization
On page 536, in place of Figure I , Scheme 5 has inadvertently been repeated; the missing Figure 1 is given below.
Diastereoselective Synthesis of 1-Hydroxy-Substituted Benzo(b) quinolidines and 11-Hydroxy-Substituted Azepino(1,2-b)isoquinolines via Hetero-Ene Cyclization. -The title compounds (VIII) and (XV) are prepared by Lewis acid-catalyzed cyclizations of (VII) and (XIV), resp., obtained from (S)-(I) by a
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