Towards a total synthesis of guanacastepene A: construction of fully functionalized AB and BC ring segments

✍ Scribed by Goverdhan Mehta; Jayant D Umarye; Vanessa Gagliardini

• Book ID: 104251907
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 87 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01597-6

✦ Synopsis

Studies directed towards the total synthesis of the diterpene antibiotic, guanacastepene A, of current interest and displaying promising biological activity against drug-resistant pathogens, has led to the acquisition of fully functionalized AB and BC ring segments of the natural product.