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Towards a functional organization of the medial temporal lobe memory system: Role of the parahippocampal and medial entorhinal cortical areas

✍ Scribed by Howard Eichenbaum; Paul A. Lipton


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
296 KB
Volume
18
Category
Article
ISSN
1050-9631

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✦ Synopsis


Abstract

Whereas substantial recent evidence has suggested to some that the medial entorhinal cortexá (MEC) plays a specialized role in spatial navigation, here we present evidence consistent with a broader role of the MEC in memory. A consideration of evidence on the anatomy and functional roles of medial temporal cortical areas and the hippocampus, and evidence from recordings from MEC neurons in rats performing a spatial memory task, suggest that the MEC may process information about both spatial and temporal context in support of episodic memory. © 2008 Wiley‐Liss, Inc.