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Towards a better QALY model

✍ Scribed by José-María Abellán-Perpiñán; José-Luis Pinto-Prades; Ildefonso Méndez-Martínez; Xabier Badía-Llach

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
171 KB
Volume
15
Category
Article
ISSN
1057-9230

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✦ Synopsis

Abstract

This paper presents a test of the predictive validity of various classes of QALY models (i.e. linear, power and exponential models). We first estimated TTO utilities for 43 EQ‐5D chronic health states and next these states were embedded in nonchronic health profiles. The chronic TTO utilities were then used to predict the responses to TTO questions with nonchronic health profiles. We find that the power QALY model clearly outperforms linear and exponential QALY models. Optimal power coefficient is 0.65. Our results suggest that TTO‐based QALY calculations may be biased. This bias can be corrected using a power QALY model. Copyright © 2006 John Wiley & Sons, Ltd.

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