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Toward the synthesis of pamamycin-607

✍ Scribed by Heiko Bernsmann; Benno Hungerhoff; Regina Fechner; Roland Fröhlich; Peter Metz


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
122 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis


Using sultone chemistry, a short and highly enantioselective synthesis of an advanced precursor for the larger hydroxy acid moiety and of the complete smaller hydroxy acid portion of the macrodiolide antibiotic pamamycin-607 has been accomplished.


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