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Toward simpler and faster genome-wide mutagenesis in mice

✍ Scribed by Wu, Sen; Ying, Guoxin; Wu, Qiang; Capecchi, Mario R


Book ID
109919580
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
364 KB
Volume
39
Category
Article
ISSN
1061-4036

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## Abstract ## Objective Susceptibility to inflammatory arthritis is determined by a complex set of environmental and genetic factors, but only a portion of the genetic effect can be explained. Conventional genome‐wide screens of arthritis models using crosses between inbred mice have been hampere