✦ LIBER ✦

Toward Rational Design of Ribonuclease Inhibitors: High-Resolution Crystal Structure of a Ribonuclease A Complex with a Potent 3‘,5‘-Pyrophosphate-Linked Dinucleotide Inhibitor †,‡

✍ Scribed by Leonidas, Demetres D.; Shapiro, Robert; Irons, Laurence I.; Russo, Nello; Acharya, K. Ravi

Book ID: 126210280
Publisher: American Chemical Society
Year: 1999
Tongue: English
Weight: 191 KB
Volume: 38
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi990900w

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Recognition of Ribonuclease A by 3′–5′-P

Recognition of Ribonuclease A by 3′–5′-Pyrophosphate-Linked Dinucleotide Inhibitors: A Molecular Dynamics/Continuum Electrostatics Analysis

✍ Polydoridis, Savvas; Leonidas, Demetres D.; Oikonomakos, Nikos G.; Archontis, Ge 📂 Article 📅 2007 🏛 Biophysical Society 🌐 English ⚖ 991 KB

High-resolution crystal structures of ri

High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors

✍ Demetres D. Leonidas; Gayatri B. Chavali; Nikos G. Oikonomakos; Evangelia D. Chr 📂 Article 📅 2009 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 638 KB

Crystal Structures of Ribonuclease A Com

Crystal Structures of Ribonuclease A Complexes with 5‘-Diphosphoadenosine 3‘-Phosphate and 5‘-Diphosphoadenosine 2‘-Phosphate at 1.7 Å Resolution †,⊥

✍ Leonidas, Demetres D.; Shapiro, Robert; Irons, Laurence I.; Russo, Nello; Achary 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 259 KB

Crystal Structure of the Kinase Domain o

Crystal Structure of the Kinase Domain of ABL in Complex with a Potent Rationally-Designed Derivative of the PP1 Inhibitor, AB129

✍ Henderson, M. Nidanie; Malecek, Kathryn E.; Makino, Deborah L.; Cao, Xiaoxian X. 📂 Article 📅 2012 🏛 Biophysical Society 🌐 English ⚖ 36 KB

The high-resolution crystal structure of

The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin

✍ Francis T.F. Tsai; Onkar M.P. Singh; Tadeusz Skarzynski; Alan J. Wonacott; Simon 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB 👁 2 views

Coumarin antibiotics, such as clorobiocin, novobiocin, and coumermycin A1, inhibit the supercoiling activity of gyrase by binding to the gyrase B (GyrB) subunit. Previous crystallographic studies of a 24-kDa Nterminal domain of GyrB from E. coli complexed with novobiocin and a cyclothialidine analog

Synthesis and crystal structure of a van

Synthesis and crystal structure of a vanadium(V) complex with a 2-hydroxy acid ligand, (NH4)2[V(OC(CH2CH3)2COO)(O)2]2: a structural model of both vanadium(V) transferrin and ribonuclease complexes with inhibitors

✍ Hambley, Trevor W.; Judd, Robert J.; Lay, Peter A. 📂 Article 📅 1992 🏛 American Chemical Society 🌐 English ⚖ 457 KB