Toward fullerene-based X-ray contrast agents: design and synthesis of non-ionic, highly-iodinated derivatives of C60

✍ Scribed by Tim Wharton; Lon J Wilson

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 87 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)02119-0

✦ Synopsis

An X-ray contrast agent precursor based on C 60 has been designed, synthesized, and characterized. The compound is the monoadduct of a malonodiamide containing six iodine atoms and eight acetal-protected alcohols with multiple hindered rotations at ambient temperature.