Toward dynamic isotopomer analysis in the rat brain in vivo: automatic quantitation of 13C NMR spectra using LCModel

Toward an in Vivo Neurochemical Profile:

Toward an in Vivo Neurochemical Profile: Quantification of 18 Metabolites in Short-Echo-Time 1H NMR Spectra of the Rat Brain

✍ Josef Pfeuffer; Ivan Tkáč; Stephen W. Provencher; Rolf Gruetter 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 203 KB

Localized in vivo 1 H NMR spectroscopy was performed with 2-ms echo time in the rat brain at 9.4 T. Frequency domain analysis with LCModel showed that the in vivo spectra can be explained by 18 metabolite model solution spectra and a highly structured background, which was attributed to resonances w