BACKGROUND. Matrix metalloproteinases (MMPs) are regulated both positively and negatively at the transcriptional level by a variety of growth factors, oncogenes, and tumor promoters. Induction of the MMP, matrilysin, by epidermal growth factor (EGF) was investigated in a human prostate cancer cell l
Toward a global characterization of the phosphoproteome in prostate cancer cells: Identification of phosphoproteins in the LNCaP cell line
β Scribed by Francesco Giorgianni; Yingxin Zhao; Dominic M. Desiderio; Sarka Beranova-Giorgianni
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 357 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0173-0835
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Genistein is a major component of soybean isoflavone and has multiple functions resulting in antitumor effects. Prostate cancer is 1 of the targets for the preventive role of genistein. We examined the effect of genistein on human prostate cancer (LNCaP and PCβ3) cells. Proliferation of
## Abstract The LNCaP cell line is a versatile and useful model suitable for the study of human prostate cancer in vitro. It has been determined that the elevation of LNCaP intracellular cyclic adenosine monophosphate (cAMP) levels through the addition of membraneβpermeable cAMP analogs, phosphodie
Voltage-gated Na / channels, classically associated with impulse conduction in excitable tissues, are also found in a variety of epithelial cell types where their possible functions are not known so well. We have previously reported expression of a voltage-gated Na / channel specifically in the high
## Abstract Insulinβlike growth factor binding proteinβ3 (IGFBPβ3), an antiproliferative and proapoptotic protein, has been shown to be upregulated by growth inhibitory concentrations of androgens in LNCaP human prostate cancer (PCa) cells, but the mechanism of regulation and the role of IGFBPβ3 in