✦ LIBER ✦
Totalsynthese von natürlichem α-Tocopherol 3. Mitteilung. Aufbau der Seitenkette mit (−)-(S)-2-Methyl-γ-butyrolacton als zentralem Baustein
✍ Scribed by Reinhard Zell
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- German
- Weight
- 464 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Total Synthesis of Natural α‐Tocopherol
(−)‐(S)‐2‐Methyl‐γ‐butyrolactone (2) represents a versatile chiral C~5~‐synthon. It serves as key intermediate in one of the syntheses of certain isoprenoid derivatives such as (R)‐dihydrocitronellol, (3__R__, 7__R__)‐hexahydrofarnesol and vitamin E of natural configurations. Their syntheses are described in detail.