Synthesis of (−)-chanoclavine I
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Nathalie Kardos; Jean-Pierre Genet
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Article
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1994
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Elsevier Science
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English
⚖ 743 KB
We then focused our attention on the asymmetric formation of the CT-Cl0 bond of the nitro acetate 3 using paRadium xero complexes 23 . The best results of this key cyclisation were obtained by using Pd(dba)g and (S,S)-CHIRAPHOS as the chiral diphosphine, in THF at teflux I8 . We optimised these resu